Erroneous correspondences between samples and their respective channel or target commonly arise in several real-world applications. For instance, whole-brain calcium imaging of freely moving organisms, multiple target tracking or multi-person contactless vital sign monitoring may be severely affected by mismatched sample-channel assignments. To systematically address this fundamental problem, we pose it as a signal reconstruction problem where we have lost correspondences between the samples and their respective channels. We show that under the assumption that the signals of interest admit a sparse representation over an overcomplete dictionary, unique signal recovery is possible. Our derivations reveal that the problem is equivalent to a structured unlabeled sensing problem without precise knowledge of the sensing matrix. Unfortunately, existing methods are neither robust to errors in the regressors nor do they exploit the structure of the problem. Therefore, we propose a novel robust two-step approach for the reconstruction of shuffled sparse signals. The performance and robustness of the proposed approach is illustrated in an application of whole-brain calcium imaging in computational neuroscience. The proposed framework can be generalized to sparse signal representations other than the ones considered in this work to be applied in a variety of real-world problems with imprecise measurement or channel assignment.
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Tourette Syndrome (TS) is a behavior disorder that onsets in childhood and is characterized by the expression of involuntary movements and sounds commonly referred to as tics. Behavioral therapy is the first-line treatment for patients with TS, and it helps patients raise awareness about tic occurrence as well as develop tic inhibition strategies. However, the limited availability of therapists and the difficulties for in-home follow up work limits its effectiveness. An automatic tic detection system that is easy to deploy could alleviate the difficulties of home-therapy by providing feedback to the patients while exercising tic awareness. In this work, we propose a novel architecture (T-Net) for automatic tic detection and classification from untrimmed videos. T-Net combines temporal detection and segmentation and operates on features that are interpretable to a clinician. We compare T-Net to several state-of-the-art systems working on deep features extracted from the raw videos and T-Net achieves comparable performance in terms of average precision while relying on interpretable features needed in clinical practice.
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Breast cancer is one of the most common cancer in women around the world. For diagnosis, pathologists evaluate biomarkers such as HER2 protein using immunohistochemistry over tissue extracted by a biopsy. Through microscopic inspection, this assessment estimates the intensity and integrity of the membrane cells' staining and scores the sample as 0, 1+, 2+, or 3+: a subjective decision that depends on the interpretation of the pathologist. This paper presents the preliminary data analysis of the annotations of three pathologists over the same set of samples obtained using 20x magnification and including $1,252$ non-overlapping biopsy patches. We evaluate the intra- and inter-expert variability achieving substantial and moderate agreement, respectively, according to Fleiss' Kappa coefficient, as a previous stage towards a generation of a HER2 breast cancer biopsy gold-standard using supervised learning from multiple pathologist annotations.
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这项工作探讨了CFGAN的再现性。 CFGan及其模型(Tagrec,MTPR和CRGAN)学会通过使用先前的交互来为TOP-N建议者生成个性化和假的偏好排名。这项工作成功复制了原始纸张中发布的结果,并讨论了CFGAN框架与原始评估中使用的模型之间的某些差异的影响。没有随机噪声和使用真实用户配置文件作为条件向量离开发电机容易发生一个退化的解决方案,其中输出矢量与输入向量相同,因此,表现为简单的AutoEncoder。该工作进一步扩展了比较CFGAN对一系列简单且众所周知的适当优化的基线的实验分析,尽管计算成本高,但仍观察CFGAN并不一致地对抗它们。为确保这些分析的再现性,这项工作描述了实验方法,并发布了所有数据集和源代码。
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We report a method to convert discrete representations of molecules to and from a multidimensional continuous representation. This model allows us to generate new molecules for efficient exploration and optimization through open-ended spaces of chemical compounds.
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